简要描述:气道阻力和肺顺应性检测系统ResistanceandCompliancePlethysmographs采用侵入式气道力学对老鼠的肺功能进行检测
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气道阻力和肺顺应性检测系统 Resistance and Compliance Plethysmographs 采用侵入式气道力学对老鼠的肺功能进行检测。
· 检测过程做一个有创型的手术;
· 检测大鼠、小鼠的多种肺功能参数,如:呼吸速率、潮气量到气道阻力和肺顺应性。
· 系统通过测量端口压、跨肺压或胸膜压以及气道中气体流速等参数,直接得出气道阻力、肺顺应性、潮气量等肺功能指标参数;
· 血压和心率的检测可以用来研究心血管反映,也可用来判断动物状态;
主要特点:
· 可选择多种给药方式(颈、尾静脉注射、雾化给药)
· 可同时检测多种参数
· 采用体积描记法,直接检测气流
· 可选配心血管参数检测模块
主要应用:
· 急性和慢性呼吸道功能障碍模型
· 综合评价的肺功能
系统采用了尾部外置的特殊描记器,可以通过尾静脉或颈静脉对动物进行注射给药,也可通过雾化的气溶胶进行吸入式给药。
具备多种给药方法:静脉注射或气溶胶
气道阻力与肺顺应性检测体积描计器
根据需要,可以额外选配心电测量功能:
· 心电图分析软件,允许用户使用特定主题的模板自定义算法。可以更准确的进行分析;
· eDacq ECG 还允许用户定义自己的 QT 校正因子;
· 可以通过传统的 ECG 导联或遥测获取信号;
· 目前正在开发 eDacq ECG 以利用新的公式来计算节拍间的不稳定性;
主要检测参数:
· 气道阻力 (有/无 插管阻力补偿)
· 动态顺应性
· 肋膜压变化
· Lung conductance
· 潮气量
· 累计体积
· 吸气时间
· 呼气时间
· 吸气流量
· 呼气流量
· 呼吸频率
· 每分通气量
· 其它参数
如需方式检测小动物的肺功能参数,可选择:
全身体积描记系统
如需检测更多肺功能参数,可选择:
多参数肺功能检测系统
参考文献:
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