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動(dòng)物氣溶膠給藥器

  • 更新時(shí)間:2023-09-02
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簡(jiǎn)要描述:氣溶膠霧化器能夠產(chǎn)生穩(wěn)定、細(xì)膩的氣溶膠,給動(dòng)物暴露實(shí)驗(yàn)或者細(xì)胞暴露實(shí)驗(yàn)提供穩(wěn)定的霧化環(huán)境

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氣溶膠霧化器能夠產(chǎn)生穩(wěn)定、細(xì)膩的氣溶膠,給動(dòng)物暴露實(shí)驗(yàn)或者細(xì)胞暴露實(shí)驗(yàn)提供穩(wěn)定的霧化環(huán)境。


氣溶膠霧化器是全身暴露或者口鼻暴露的重要組成部分,可配合暴露箱或者暴露塔使用,將藥物霧化后的氣溶膠推送到暴露內(nèi),并持續(xù)霧化和維持暴露箱內(nèi)一定的氣溶膠濃度。

我們可以提供Aerogen Pro霧化器和Aerogen Solo霧化器:設(shè)備采用鈀合金振動(dòng)網(wǎng)格技術(shù),中心孔板直徑5mm,均勻分布著1000個(gè)精密成形微孔,每秒振動(dòng)128,000次,形成非常有利于沉淀入肺部沉積的氣溶膠顆粒滴。


 

 

型號(hào):Aerogen Pro


 


 

型號(hào):Aerogen Solo


產(chǎn)品主要優(yōu)勢(shì):


· 霧化劑量??;
· 粒度分布和顆粒物體濃度具有高度的可重復(fù)性;
· 隨時(shí)可填充藥物,也可以加配注射泵自動(dòng)添加藥物;
· 抗腐蝕外殼設(shè)計(jì),持久耐用;
· 高度集成化、體積小巧;
· 操作簡(jiǎn)單,無(wú)需復(fù)雜的培訓(xùn)工作;



·小型:Volume Median Diameter(VMD)
· 霧化速率:>0.1mL/min
· 顆粒尺寸:VMD (體積中值直徑)介于2.5μm and 4.0μm
· 藥物殘余量:<0.1mL 

· 液體霧化氣溶膠在科學(xué)研究、藥物開(kāi)發(fā)、質(zhì)量檢測(cè)中有很多應(yīng)用;



霧化的顆粒物粒徑分布:



霧化的顆粒物粒徑分布:  

根據(jù)需要,您還可以選擇BGI Collison氣溶膠發(fā)生器


有多種規(guī)格和尺寸可供選擇,可以根據(jù)客戶(hù)的需求進(jìn)行定制:
 


 


我們還可以根據(jù)實(shí)驗(yàn)室需求,推薦更適合的霧化染毒搭配方案,敬請(qǐng)。

粉塵氣溶膠發(fā)生器,可對(duì)粉塵進(jìn)行霧化,產(chǎn)生穩(wěn)定的粉塵氣溶膠

 


氣溶膠濃度測(cè)量?jī)x,用于對(duì)暴露環(huán)境的氣溶膠濃度進(jìn)行實(shí)時(shí)測(cè)量

 


動(dòng)物暴露染毒箱,用于對(duì)動(dòng)物進(jìn)行長(zhǎng)時(shí)間的氣溶膠暴露

 



氣溶膠發(fā)生器部分參考文獻(xiàn):
1.Sidler-Moix A L, Di Paolo E R, Dolci U, et al. Physicochemical aspects and efficiency of albuterol nebulization: comparison of three aerosol types in an in vitro pediatric model[J]. Respiratory care, 2015, 60(1): 38-46.
2.Hassan A, Rabea H, Hussein R R S, et al. In-vitro characterization of the aerosolized dose during non-invasive automatic continuous positive airway pressure ventilation[J]. Pulmonary Therapy, 2016, 2: 115-126.
3.ElHansy M H E, Boules M E, El Essawy A F M, et al. Inhaled salbutamol dose delivered by jet nebulizer, vibrating mesh nebulizer and metered dose inhaler with spacer during invasive mechanical ventilation[J]. Pulmonary pharmacology & therapeutics, 2017, 45: 159-163.
4.Fang T P, Lin H L, Wan G H, et al. In vitro evaluation of aerosolized delivery of various medications during mechanical ventilation[J]. 2017.
5.Abdelrahim M E A, Saeed H, Harb H S, et al. The Aerosol Generators Available for Critically Ill Patient[J]. Essentials of Aerosol Therapy in Critically ill Patients, 2021: 115-135.
6.ElHansy M H E, Boules M E, El Essawy A F M, et al. Inhaled salbutamol dose delivered by jet nebulizer, vibrating mesh nebulizer and metered dose inhaler with spacer during invasive mechanical ventilation[J]. Pulmonary pharmacology & therapeutics, 2017, 45: 159-163.
7.Gowda A A, Cuccia A D, Smaldone G C. Reliability of vibrating mesh technology[J]. Respiratory Care, 2017, 62(1): 65-69.
8.Gerde P, Nowenwik M, Sj?berg C O, et al. Adapting the aerogen mesh nebulizer for dried aerosol exposures using the preciseinhale platform[J]. Journal of aerosol medicine and pulmonary drug delivery, 2020, 33(2): 116-126.
9.Michotte J B, Staderini E, Le Pennec D, et al. In vitro comparison of a vibrating mesh nebulizer operating in inspiratory synchronized and continuous nebulization modes during noninvasive ventilation[J]. Journal of aerosol medicine and pulmonary drug delivery, 2016, 29(4): 328-336.
10.Cahill R A, Dalli J, Khan M, et al. Solving the problems of gas leakage at laparoscopy[J]. British Journal of Surgery, 2020, 107(11): 1401-1405.
11.Sarhan R M, Elberry A A, Abdelwahab N S, et al. Effect of a nebulizer holding chamber on aerosol delivery[J]. Respiratory care, 2018, 63(9): 1125-1131.



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